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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX8
All Species:
8.48
Human Site:
S14
Identified Species:
15.56
UniProt:
Q14562
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14562
NP_004932.1
1220
139315
S14
M
A
G
A
L
I
G
S
E
P
G
P
A
E
E
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537627
1216
138553
T14
V
A
G
A
V
T
G
T
E
L
G
P
A
E
E
Cat
Felis silvestris
Mouse
Mus musculus
A2A4P0
1244
142553
S14
A
A
G
V
L
M
G
S
E
P
G
P
A
E
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418105
1076
123154
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002663993
1210
138002
E8
M
A
E
I
G
E
D
E
L
K
K
L
E
Y
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610928
1242
141917
N27
L
D
N
H
L
G
I
N
D
K
D
L
A
E
F
Honey Bee
Apis mellifera
XP_623289
1192
136394
H9
D
E
V
A
K
L
E
H
L
S
L
V
S
K
I
Nematode Worm
Caenorhab. elegans
Q09530
1200
135741
S8
M
D
Q
L
E
H
L
S
L
V
S
K
V
L
S
Sea Urchin
Strong. purpuratus
O17438
455
51461
Poplar Tree
Populus trichocarpa
XP_002318357
1207
137837
A9
V
A
A
G
E
N
D
A
G
L
K
K
L
E
Y
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
L9
E
K
E
E
L
N
K
L
N
H
L
S
L
V
S
Baker's Yeast
Sacchar. cerevisiae
P24384
1145
129992
G9
S
D
I
S
K
L
I
G
A
I
V
G
S
D
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40
N.A.
98.5
N.A.
96.8
N.A.
N.A.
N.A.
84
N.A.
91.1
N.A.
69.4
71.8
61.3
21.9
Protein Similarity:
100
59
N.A.
99.1
N.A.
97.3
N.A.
N.A.
N.A.
86.8
N.A.
94.5
N.A.
82
83.9
75.4
28.8
P-Site Identity:
100
0
N.A.
66.6
N.A.
80
N.A.
N.A.
N.A.
0
N.A.
13.3
N.A.
20
6.6
13.3
0
P-Site Similarity:
100
0
N.A.
86.6
N.A.
86.6
N.A.
N.A.
N.A.
0
N.A.
13.3
N.A.
40
26.6
13.3
0
Percent
Protein Identity:
59.1
N.A.
N.A.
59.3
44.2
N.A.
Protein Similarity:
75
N.A.
N.A.
75.4
62.8
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
6.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
39
8
24
0
0
0
8
8
0
0
0
31
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
24
0
0
0
0
16
0
8
0
8
0
0
8
8
% D
% Glu:
8
8
16
8
16
8
8
8
24
0
0
0
8
39
24
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
24
8
8
8
24
8
8
0
24
8
0
0
0
% G
% His:
0
0
0
8
0
8
0
8
0
8
0
0
0
0
0
% H
% Ile:
0
0
8
8
0
8
16
0
0
8
0
0
0
0
8
% I
% Lys:
0
8
0
0
16
0
8
0
0
16
16
16
0
8
0
% K
% Leu:
8
0
0
8
31
16
8
8
24
16
16
16
16
8
8
% L
% Met:
24
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
16
0
8
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
16
0
24
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
8
0
0
0
24
0
8
8
8
16
0
16
% S
% Thr:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% T
% Val:
16
0
8
8
8
0
0
0
0
8
8
8
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _